Every year, the Geneva-based World Economic Forum honors as "Tech Pioneers" anywhere from 30 to 50 companies offering new technologies or business models that could advance the global economy and have a positive impact on people's lives. More than half of this year's 34 honorees hail from outside the U.S. Twelve come from Europe, three from Asia, two from Africa, and one from South America. The companies were chosen by an independent panel of venture capitalists and industry experts.
Tech Leaders of Tomorrow
Some former winners such as Google helped give a leg up to the crop of 2009 Technology Pioneers chosen by the World Economic Forum
The group of 20 young, fresh-faced computer programmers in jeans and polo shirts embossed with the company logo could have been with any Silicon Valley startup. But the team, lined up in New Delhi in July 2007 for a portrait taken by a news photographer, work for a Swiss company called Nivio, which employs more than 85% of its engineers and designers in India. The headline over the photo crows: "Indians invented world's first Windows-based online desktop."
Nivio is one of 34 companies chosen this year by the Geneva-based World Economic Forum to be among its 2009 Technology Pioneers—companies offering new technologies or business models that could advance the global economy and positively affect peoples' lives. It's a perfect example of how the technology business is evolving.
This year marks the 10th anniversary of the forum's Tech Pioneers program. All the winners to date have made their mark in areas such as information technology, biotech, and energy. Some of them even had a hand in the success of this year's crop.
A Geographically Diverse Class
Max Levchin, a co-founder of PayPal (EBAY), a Tech Pioneer in 2001, is the founder of one of this year's winners, Slide, the inventor of a number of popular social networking applications, including "sheep throwing," a way that Facebook users get attention from one another. And search engine giant Google (GOOG), a winner in 2001, is an investor in three of the 2009 Tech Pioneers: a solar thermal energy company called BrightSource Energy, a wireless technology company called Ubiquisys, and CURRENT Group, which makes software that lets utilities manage their grids in real time.
But what really distinguishes this year's class is the number of companies based in new and different places. "We have never had such a geographically diverse class as this year, with more than 10% of our companies coming from emerging markets," says Rodolfo Lara, head of the forum's Tech Pioneers program. "We believe in five years' time we will probably have as many Tech Pioneers from emerging markets as we will have from Europe."
Indeed, innovative approaches to some of the world's thorniest problems are expected increasingly to come from emerging economies. These will be the biggest markets going forward, and with some of the biggest challenges. The argument goes, those who live there are the best placed to design the products and services this part of the world needs. Industry observers believe that many of those innovations also will end up being embraced by the developed world, so the next Google—or the next PayPal—could come from India or China.
Cross-Fertilization
This year, two of the Tech Pioneers hailed from Africa, one from China, one from India, and one from Latin America. But those figures are somewhat deceiving. Other companies in this year's class have their roots in the developing world. BioMedica Diagnostics, for example, a biotech based in Nova Scotia, Canada, was founded by Abdullah Kirumira, a Uganda native and trained chemist. He is using the proceeds from a lab test he developed for affluent countries, called QuikCoag, to help fund development of desperately needed lab tests to help save the lives of some of the world's poorest people—what he calls "cross-fertilization."
Switzerland-based Nivio was founded by 25-year-old Sacchin Duggal, whose parents emigrated from India to England. Duggal, who was trained as an information systems engineer at Imperial College in England, says he was drawn to his parent's homeland. So when he and his college friend, Saurabh Dhoot, had their "lightbulb moment" and decided to form Nivio, they turned to programmers in India to help them realize their dream.
Nivio provides access, via any standard Internet browser, to a full-featured personal Microsoft (MSFT) Windows desktop. That means people with old or cheap PCs can use sophisticated, state-of-the-art programs, running remotely, as well as store data and share files with other users. It also allows individuals and small businesses to temporarily "rent" the use of an expensive program such as Word or Excel without having to buy it.
Rolling Out Kiosks
The company also has launched a low-cost computing device called the Nivio Companion, a $100 box that plugs into a computer monitor or TV and can gain access to Nivio's Windows desktop. Nivio doesn't plan on staying in the hardware business, says Duggal. The company would prefer that its software services be bundled with established manufacturers' computing devices. It hopes to strike deals to get a "Nivio Inside" sticker on machines made by others.
The company is headquartered in Switzerland because of data security. Since users store all of their data with Nivio, rather than on their own computers, they need reassurances, says Duggal. The company already has customers in places stretching from China to Brazil and is about to launch, in partnership with mobile-service provider Bharti Airtel, the rollout of Internet kiosks across India that will be powered by Nivio.
Nivio has some stiff competition, including Google Apps. But Duggal says Nivio's approach is superior because it comes closer to giving users a familiar desktop and applications. In any case, he says his goal isn't merely to beat the Silicon Valley-based search engine giant. "If we make it to Google's size, I would be happy but I wouldn't be satisfied," he says. "If we do this right, we should be the world's biggest software company." Spoken like a true tech pioneer. It's that kind of moxie that helped previous Tech Pioneers to get where they are today.
Advanced Track & Trace
Rueil-Malmaison, France
Anticounterfeiting tracking and tracing technology
Chief scientist: Justin Picard, 35
Advanced Track & Trace makes Seal Vector, a digital anticounterfeiting and tracking technology that can be printed or marked on virtually any material. Think of it as a bar code that "leaks" data when copied. With a simple scan, copies can be detected because they contain less data than the original. Corporate customers include beauty products group L'Oréal, pharmaceutical companies, and French wine producers.
Etsy
Brooklyn, N.Y.
Online marketplace
Chief creative officer: Robert Kalin, 28
Etsy is a digital marketplace for buyers and sellers of handmade goods ranging from robots to rocking horses. The idea is "to empower small businesses and keep the big guys out," says Kalin, the company's founder. Etsy has attracted 200,000 sellers from 100 countries and expects to handle $100 million in transactions this year. It charges 20¢ for each listing, and sellers who want to showcase their wares can pay an additional $7 to $15 a day for advertising. Etsy also takes 3.5% of the price of every item sold.
Gameforge
Karlsruhe, Germany
Online games
CEO: Klaas Kersting 28
Intergalactic conquests, gladiator quests, and gothic adventures with vampires and werewolves have attracted more than 65 million players in 36 countries to register for Gameforge's 25 multiplayer online games. The games, available in 50 languages, are free and work on any device that has an Internet connection and a browser. The company makes its money from selling features that give players an edge, such as virtual magic swords. It's forecasting more than $130 million in revenues in 2009.
BrightSource Energy
Oakland, Calif.
Solar energy
CEO: John Woolard, 43
BrightSource Energy's solar thermal technology uses thousands of small mirrors to reflect sunlight onto a boiler atop a tower to produce high-temperature steam, which is then piped to a turbine that generates electricity. The company claims its system, originally developed in Israel, offers higher operating efficiencies than other solar thermal technologies, making it competitive with fossil fuels. The company has raised more than $160 million from investors.
Mobile Healthcare
Tokyo
Health care
CEO: James Hiroshi Nakagawa, 44
When one of his friends was diagnosed with diabetes and placed on a restricted diet, Nakagawa was surprised to discover how difficult it was to obtain basic information about the calories in ordinary food. This sparked the idea of Lifewatcher, a health management service for people with so-called "lifestyle diseases." The service not only allows people to look up nutrition information via the Internet or their mobile phones, but also monitors users' conditions as they log in their blood sugar levels, calorie intake, exercise, and other variables.
Tideway Systems
London
IT management
CEO: Richard Muirhead, 36
Call it Google for IT managers. Founded by serial entrepreneur Muirhead, Tideway Systems uses artificial-intelligence techniques to map corporate IT infrastructures. Having an up-to-the-minute view of their networks can help corporations cut data center costs and reduce downtime caused by IT troubles. Tideway has raised venture capital from Scottish Equity Partners, Apax Partners, and Accel Partners.
BioMedica Diagnostics
Windsor, N.S., Canada
Health care
CEO: Abdullah Kirumira, 53
BioMedica developed a lab test for blood clots, QuikCoag, that is widely sold in developed countries. Now Kirumira, a Uganda native and trained chemist, is using proceeds from QuikCoag to improve medical diagnostics in some of the world's poorest countries. He has developed a testing kit, Complete Lab, that can be set up in primitive clinics to test for more than 90 diseases, from HIV to malaria.
SpinVox
London
Messaging
CEO: Christina Domecq, 32
SpinVox's technology uses a combination of voice recognition, artificial intelligence, and natural liguistics to convert voice messages to text. Then it delivers the messages in a variety of forms, including e-mails, text messages, blog posts, or postings on social-network sites. SpinVox has deals with operators around the globe and expects to reach 100 million customers by 2009.
NovaTorque
Sunnyvale, Calif.
Electric motors
Founder and CTO: John Petro, 57
NovaTorque has developed a patented electric motor technology that it says is 10% to 30% more efficient than conventional electric motors. Motors account for about half of all electric energy consumption, so even small efficiency improvements could save tens of billions annually in energy costs. NovaTorque motors have a unique conical structure that the company says are more compact and run cooler than conventional motors.
Slide
San Francisco
Social networking
CEO: Max Levchin, 33
Slide helps put the fun in online applications. Its first product, available on social networks like Bebo, MySpace, and Orkut, allows users to upload, decorate, and share photos as slide shows. It's also behind two of the most popular widgets on Facebook: Top Friends, which lets users install quick links to their virtual buddies, and FunWall, an interactive billboard that lets users share videos, posters, and fun messages. Slide is perhaps best known for SuperPoke!, an application offering virtual hijinks like "sheep throwing" and "trout slap."
RecycleBank
New York
Recycling
CEO: Ron Gonen, 33
RecycleBank has launched programs in 15 states that motivate people to recycle household waste. It provides each household with a container featuring an embedded Radio Frequency Identification (RFID) tag. When recycling crews empty the container, scanners on their trucks record the weight of the contents and transmit the information to a RecycleBank account. Households accumulate reward points that can be used for purchases at more than 800 retailers, including Target and IKEA.
Ubiquisys
Swindon, England
Telecommunications
CEO: Chris Gilbert, 51
Ubiquisys is a pioneer in femtocell technology, which lets mobile-phone users plug into broadband connections to improve their reception while using their handsets at home or in the office. Besides more reliable reception, users can enjoy higher-quality mobile Internet services while taking advantage of cheaper rates. Thirteen mobile operators are currently trying out the service, and three are expected to launch services in Europe by next March.
Mint.com
Mountain View, Calif.
Personal finance services
Founder and CEO: Aaron Patzer, 28
Mint.com makes money by helping consumers make smarter financial decisions. Its four patent-pending technologies and algorithms help users understand where they're spending money, create budgets, and find ways to save. Launched in September 2007, the free online service already has attracted more than 600,000 consumers. Mint.com provides e-mail and text message alerts, notifying users of low account balances and upcoming bills and fees. The company earns its money from referral fees and advertising.
Mojix
Los Angeles
Radio-frequency ID tags
CEO: Ramin Sadr, 49
Mojix was founded in 2004 by a team of former NASA scientists and engineers to apply breakthroughs in deep space communications to radio-frequency ID systems. With traditional systems, RFID tags can't be read unless the scanning device is nearby. Mojix applies new signal-processing technologies to enable long-range detection, even when signals are weak. Mojix's SpaceTime Array Reader claims to deliver a 100,000-times improvement in indoor receiver sensitivity, and can handle numerous applications across an entire factory,
SemiLEDS
Boise, Idaho
Efficient lighting
CEO: Trung Tri Doan, 50
SemiLEDs, with operations in the U.S. and Taiwan, aims to provide the first effective light-emitting-diode (LED) solutions for mass-market lighting. LEDs, though far more efficient than conventional incandescent lighting, until now have been too costly for widespread use. SemiLEDS, founded by a semiconductor industry veteran, tackled the problem by switching to a low-cost chip built on a flexible copper alloy.
Brightcove
Cambridge, Mass.
Broadband media and online video
CEO: Jeremy Allaire, 37
Brightcove has developed an open Web-based software service that allows media groups of all sizes to publish, distribute, and make money from online video through their own Web sites and across the Internet. Hundreds of media companies use its technology to deliver tens of millions of videos to consumers worldwide. The company has raised $91 million from investors including Accel Partners, Allen & Co., Hearst Corp., the New York Times Co., and America Online.
Qifang
Shanghai, China
Finance
CEO: Calvin Chin, 35
Qifang has developed an online microfinance site to help aspiring Chinese university students pay for their schooling. Students who can't afford tuition post their profiles on the site in hopes of catching the attention of well-off individuals or businesses who could lend them money. Qifang brokers the transactions and helps manage the loan portfolios, earning money by charging a 2% fee on each loan.
mPedigree
Accra, Ghana
Anticounterfeiting
CEO: Bright Simons, 27
mPedigree offers consumers a service to instantly verify the authenticity of drugs at the point of purchase. Pharmaceutical companies emboss special codes on drug packaging that are recorded in mPedigree's database. When consumers purchase drugs, they scratch off a panel to reveal the code and send it via text message over a standard mobile phone. Within five seconds, they get a reply indicating whether the code is genuine.
Cows to Kilowatts Partnership Ltd.
Ibadan, Nigeria
Biofuels
CEO: Joseph Adelegan, 41
Cows to Kilowatts has found a clean way to convert slaughterhouse waste into biofuel for household cooking and electricity. Instead of smelly, inefficient traditional waste-treatment methods, Cows to Kilowatts offers a bioreactor system that turns organic waste into cheap, nonpolluting fuel. As a bonus, the system churns out environmentally friendly fertilizer from the remaining sludge.
Nivio
Aigle, Switzerland
Software services
CEO: Sachin Duggal, 25
Need specialized software for a short-term project? No need to buy it; Nivio will rent it to you. The company provides customers with a personalized Windows desktop, outfitted with whatever software they request, for as long as they need it. It also makes a low-cost computing device. The company is about to launch, in partnership with Indian telcom operator Bharti Airtel, a rollout of Internet kiosks across India that will be powered by Nivio.
MorphoSys
Martinsried, Germany
Biotechnology
CEO: Simon Moroney, 49
MorphoSys is trying to reproduce the human immune response in a test tube. The company, which was founded in 1992 and went public on the Frankfurt stock exchange in 1999, boasts a library of more than 10 billion human antibodies that can be optimized to target specific diseases. It has several drugs in phase-one clinical trials, one to combat Alzheimer's disease, two aimed at cancer, and another for arthritis.
JiGrahak Mobility Solutions
Bangalore, India
Mobile commerce
CEO: Sourabh Jain, 31
JiGrahak is behind ngpay, the brand name of a free mobile-commerce service that allows consumers in India to shop, order meals, make charitable donations, do their banking, and pay their bills, among other things. Launched last February, ngpay already has attracted more than 230,000 users and has become the largest channel for mobile-based transactions with Indian Railways and HDFC Bank, and for movie ticketing. The company expects to have 1 million users by mid-2009.
CURRENT Group
Germantown, Md.
Energy efficiency
CEO: Tom Casey, 56
CURRENT provides utility companies with high-speed communications and sensing and analytic software that allows them to manage their grids in real time. Better management yields environmental benefits, too, because electric power generation produces 40% of global carbon-dioxide emissions. CURRENT, founded in 2000, started by offering broadband access via electric lines. It has raised some $300 million from blue chip investors including Google and Goldman Sachs.
GreenPeak Technologies
Utrecht, Netherlands
Green wireless technology
CEO: Cees Links, 51
It sounds like a simple way to save energy: A wireless sensor network in your house would automatically shut off lights and turn down heating when you leave a room. But such networks have proven costly and cumbersome. GreenPeak has developed a communication technology for wireless sensor networks that can use energy harvested from the environment rather than from batteries. It claims to be the first Wi-Fi-based controller capable of providing a maintenance-free sensor network.
Lemnis Lighting
Amsterdam, Netherlands
Lighting
CEO: Frans Otten, 41
Lemnis Lighting was started by Otten and Warner Philips, both great-grandsons of the founder of Royal Philips Electronics. It aims to achieve affordable zero carbon-emission lighting by using light-emitting diodes (LEDs) in new ways. The company is striking deals to have its energy-saving bulbs distributed through electric companies.
Recycla Chile
Santiago, Chile
Recycling
CEO: Fernando Nilo, 44
Recycla Chile was the first company in Latin America to recycle discarded computers, television, mobile phones, fax machines, and other electronic gizmos. Such e-trash accounts for 70% of toxic waste in landfills. Electronics makers collect old devices from business customers and send them to Recycla, which extracts valuable materials. Most of the work is done by former prison inmates, whom the company hires to help them reintegrate into society.
ZPower
Camarillo, Calif.
Batteries
CEO: Ross Dueber, 48
ZPower uses advanced polymers, nanotechnology, power electronics, and processing methods to create a superefficient rechargeable battery for consumer electronic devices. The technology isn't compatible with existing devices that use lithium-ion batteries, but next-generation laptops, mobile phones, and other devices coming to market as early as 2009 will use it. Dueber says Zpower batteries can as much as double the time between recharges.
Virent
Madison, Wis.
Biofuels
Chief technology officer: Randy Cortright, 53
Virent has developed technology to convert plant sugars into hydrocarbon molecules, yielding diesel, jet fuel, chemicals, and other products normally made from petroleum. The company claims its process is more efficient than traditional biofuel methods, such as ethanol fermentation. Virent has raised more than $30 million from investors and is collaborating with Royal Dutch Shell to produce biogasoline.
Alnylam Pharmaceuticals
Cambridge, Mass.
Pharmaceuticals
CEO: John Maraganore, 46
Alnylam is developing a new class of medicines based on a discovery known as RNA interference (RNAi), heralded as a major scientific breakthrough. RNAi is a natural cellular mechanism that can silence specific disease-causing genes. Alnylam is teaming with major drugmakers to develop treatments for liver cancer, Huntington's disease, and other ailments.
AC Immune
Lausanne, Switzerland
Biotechnology
CEO: Andrea Pfeifer, 51
This company, co-founded by a Nobel Laureate in chemistry in 2003, is working on treatments for Alzheimer's disease. Alzheimer's is caused by abnormal aggregations of proteins, called plaques, that block normal brain functioning. AC Immune is developing therapies to dissolve the plaques and inhibit their formation. Clinical trials of three such treatments began this year.
Phase Forward
Waltham, Mass.
Health care
CEO: Robert Weiler, 57
Roughly half of all clinical drug trials still rely on paper recordkeeping. Phase Forward offers software and services to automate the process, reducing the chance of human error and making it easier for researchers to spot potential side effects that emerge during trials. Phase Forward products have already been used by drugmakers and biotech companies in more than 10,000 clinical trials involving 1 million participants.
Intercell
Vienna, Austria
Biotechnology
CEO: Gerd Zettlemeissl, 53
Intercell is developing vaccines that target viruses and bacteria causing a wide range of ailments, from influenza and tuberculosis to Japanese encephalitis. The company analyzes the molecular structures of disease-causing pathogens, then chemically synthesizes them into "smart" vaccines that can help the immune system recognize and kill the pathogens. It also adds "immunizers" that stimulate T-Cells, a type of blood cell that protects the body from infection.
TraceTracker Innovation
Oslo, Norway
Food safety
CEO: Ole-Henning Fredriksen, 45
TraceTracker is creating a kind of global information exchange for the food industry. Its global traceability network, GTNet, enables producers, distributors, and retailers to exchange information about food products, tracing them from raw ingredients to the supermarket shelf. A franchise in Germany which licenses Walt Disney Co.'s brand for use on food products uses GTNet to provide an online tool for consumers, allowing them to use Google Maps to see where ingredients came from.
Proteus Biomedical
Redwood City, Calif.
Medical technology
CEO: Andrew Thompson, 45
Proteus makes tiny microchips implanted in pills that record and transmit how the body reacts. The data is stored temporarily in a patch placed on the patient's skin, then periodically downloaded to the patient's mobile phone so it can be forwarded to the doctor. The system can be used for long-distance monitoring of patients with cardiac problems, as well as making sure that people with infectious diseases or mental illnesses
Tech Leaders of Tomorrow
Some former winners such as Google helped give a leg up to the crop of 2009 Technology Pioneers chosen by the World Economic Forum
The group of 20 young, fresh-faced computer programmers in jeans and polo shirts embossed with the company logo could have been with any Silicon Valley startup. But the team, lined up in New Delhi in July 2007 for a portrait taken by a news photographer, work for a Swiss company called Nivio, which employs more than 85% of its engineers and designers in India. The headline over the photo crows: "Indians invented world's first Windows-based online desktop."
Nivio is one of 34 companies chosen this year by the Geneva-based World Economic Forum to be among its 2009 Technology Pioneers—companies offering new technologies or business models that could advance the global economy and positively affect peoples' lives. It's a perfect example of how the technology business is evolving.
This year marks the 10th anniversary of the forum's Tech Pioneers program. All the winners to date have made their mark in areas such as information technology, biotech, and energy. Some of them even had a hand in the success of this year's crop.
A Geographically Diverse Class
Max Levchin, a co-founder of PayPal (EBAY), a Tech Pioneer in 2001, is the founder of one of this year's winners, Slide, the inventor of a number of popular social networking applications, including "sheep throwing," a way that Facebook users get attention from one another. And search engine giant Google (GOOG), a winner in 2001, is an investor in three of the 2009 Tech Pioneers: a solar thermal energy company called BrightSource Energy, a wireless technology company called Ubiquisys, and CURRENT Group, which makes software that lets utilities manage their grids in real time.
But what really distinguishes this year's class is the number of companies based in new and different places. "We have never had such a geographically diverse class as this year, with more than 10% of our companies coming from emerging markets," says Rodolfo Lara, head of the forum's Tech Pioneers program. "We believe in five years' time we will probably have as many Tech Pioneers from emerging markets as we will have from Europe."
Indeed, innovative approaches to some of the world's thorniest problems are expected increasingly to come from emerging economies. These will be the biggest markets going forward, and with some of the biggest challenges. The argument goes, those who live there are the best placed to design the products and services this part of the world needs. Industry observers believe that many of those innovations also will end up being embraced by the developed world, so the next Google—or the next PayPal—could come from India or China.
Cross-Fertilization
This year, two of the Tech Pioneers hailed from Africa, one from China, one from India, and one from Latin America. But those figures are somewhat deceiving. Other companies in this year's class have their roots in the developing world. BioMedica Diagnostics, for example, a biotech based in Nova Scotia, Canada, was founded by Abdullah Kirumira, a Uganda native and trained chemist. He is using the proceeds from a lab test he developed for affluent countries, called QuikCoag, to help fund development of desperately needed lab tests to help save the lives of some of the world's poorest people—what he calls "cross-fertilization."
Switzerland-based Nivio was founded by 25-year-old Sacchin Duggal, whose parents emigrated from India to England. Duggal, who was trained as an information systems engineer at Imperial College in England, says he was drawn to his parent's homeland. So when he and his college friend, Saurabh Dhoot, had their "lightbulb moment" and decided to form Nivio, they turned to programmers in India to help them realize their dream.
Nivio provides access, via any standard Internet browser, to a full-featured personal Microsoft (MSFT) Windows desktop. That means people with old or cheap PCs can use sophisticated, state-of-the-art programs, running remotely, as well as store data and share files with other users. It also allows individuals and small businesses to temporarily "rent" the use of an expensive program such as Word or Excel without having to buy it.
Rolling Out Kiosks
The company also has launched a low-cost computing device called the Nivio Companion, a $100 box that plugs into a computer monitor or TV and can gain access to Nivio's Windows desktop. Nivio doesn't plan on staying in the hardware business, says Duggal. The company would prefer that its software services be bundled with established manufacturers' computing devices. It hopes to strike deals to get a "Nivio Inside" sticker on machines made by others.
The company is headquartered in Switzerland because of data security. Since users store all of their data with Nivio, rather than on their own computers, they need reassurances, says Duggal. The company already has customers in places stretching from China to Brazil and is about to launch, in partnership with mobile-service provider Bharti Airtel, the rollout of Internet kiosks across India that will be powered by Nivio.
Nivio has some stiff competition, including Google Apps. But Duggal says Nivio's approach is superior because it comes closer to giving users a familiar desktop and applications. In any case, he says his goal isn't merely to beat the Silicon Valley-based search engine giant. "If we make it to Google's size, I would be happy but I wouldn't be satisfied," he says. "If we do this right, we should be the world's biggest software company." Spoken like a true tech pioneer. It's that kind of moxie that helped previous Tech Pioneers to get where they are today.
Advanced Track & Trace
Rueil-Malmaison, France
Anticounterfeiting tracking and tracing technology
Chief scientist: Justin Picard, 35
Advanced Track & Trace makes Seal Vector, a digital anticounterfeiting and tracking technology that can be printed or marked on virtually any material. Think of it as a bar code that "leaks" data when copied. With a simple scan, copies can be detected because they contain less data than the original. Corporate customers include beauty products group L'Oréal, pharmaceutical companies, and French wine producers.
Etsy
Brooklyn, N.Y.
Online marketplace
Chief creative officer: Robert Kalin, 28
Etsy is a digital marketplace for buyers and sellers of handmade goods ranging from robots to rocking horses. The idea is "to empower small businesses and keep the big guys out," says Kalin, the company's founder. Etsy has attracted 200,000 sellers from 100 countries and expects to handle $100 million in transactions this year. It charges 20¢ for each listing, and sellers who want to showcase their wares can pay an additional $7 to $15 a day for advertising. Etsy also takes 3.5% of the price of every item sold.
Gameforge
Karlsruhe, Germany
Online games
CEO: Klaas Kersting 28
Intergalactic conquests, gladiator quests, and gothic adventures with vampires and werewolves have attracted more than 65 million players in 36 countries to register for Gameforge's 25 multiplayer online games. The games, available in 50 languages, are free and work on any device that has an Internet connection and a browser. The company makes its money from selling features that give players an edge, such as virtual magic swords. It's forecasting more than $130 million in revenues in 2009.
BrightSource Energy
Oakland, Calif.
Solar energy
CEO: John Woolard, 43
BrightSource Energy's solar thermal technology uses thousands of small mirrors to reflect sunlight onto a boiler atop a tower to produce high-temperature steam, which is then piped to a turbine that generates electricity. The company claims its system, originally developed in Israel, offers higher operating efficiencies than other solar thermal technologies, making it competitive with fossil fuels. The company has raised more than $160 million from investors.
Mobile Healthcare
Tokyo
Health care
CEO: James Hiroshi Nakagawa, 44
When one of his friends was diagnosed with diabetes and placed on a restricted diet, Nakagawa was surprised to discover how difficult it was to obtain basic information about the calories in ordinary food. This sparked the idea of Lifewatcher, a health management service for people with so-called "lifestyle diseases." The service not only allows people to look up nutrition information via the Internet or their mobile phones, but also monitors users' conditions as they log in their blood sugar levels, calorie intake, exercise, and other variables.
Tideway Systems
London
IT management
CEO: Richard Muirhead, 36
Call it Google for IT managers. Founded by serial entrepreneur Muirhead, Tideway Systems uses artificial-intelligence techniques to map corporate IT infrastructures. Having an up-to-the-minute view of their networks can help corporations cut data center costs and reduce downtime caused by IT troubles. Tideway has raised venture capital from Scottish Equity Partners, Apax Partners, and Accel Partners.
BioMedica Diagnostics
Windsor, N.S., Canada
Health care
CEO: Abdullah Kirumira, 53
BioMedica developed a lab test for blood clots, QuikCoag, that is widely sold in developed countries. Now Kirumira, a Uganda native and trained chemist, is using proceeds from QuikCoag to improve medical diagnostics in some of the world's poorest countries. He has developed a testing kit, Complete Lab, that can be set up in primitive clinics to test for more than 90 diseases, from HIV to malaria.
SpinVox
London
Messaging
CEO: Christina Domecq, 32
SpinVox's technology uses a combination of voice recognition, artificial intelligence, and natural liguistics to convert voice messages to text. Then it delivers the messages in a variety of forms, including e-mails, text messages, blog posts, or postings on social-network sites. SpinVox has deals with operators around the globe and expects to reach 100 million customers by 2009.
NovaTorque
Sunnyvale, Calif.
Electric motors
Founder and CTO: John Petro, 57
NovaTorque has developed a patented electric motor technology that it says is 10% to 30% more efficient than conventional electric motors. Motors account for about half of all electric energy consumption, so even small efficiency improvements could save tens of billions annually in energy costs. NovaTorque motors have a unique conical structure that the company says are more compact and run cooler than conventional motors.
Slide
San Francisco
Social networking
CEO: Max Levchin, 33
Slide helps put the fun in online applications. Its first product, available on social networks like Bebo, MySpace, and Orkut, allows users to upload, decorate, and share photos as slide shows. It's also behind two of the most popular widgets on Facebook: Top Friends, which lets users install quick links to their virtual buddies, and FunWall, an interactive billboard that lets users share videos, posters, and fun messages. Slide is perhaps best known for SuperPoke!, an application offering virtual hijinks like "sheep throwing" and "trout slap."
RecycleBank
New York
Recycling
CEO: Ron Gonen, 33
RecycleBank has launched programs in 15 states that motivate people to recycle household waste. It provides each household with a container featuring an embedded Radio Frequency Identification (RFID) tag. When recycling crews empty the container, scanners on their trucks record the weight of the contents and transmit the information to a RecycleBank account. Households accumulate reward points that can be used for purchases at more than 800 retailers, including Target and IKEA.
Ubiquisys
Swindon, England
Telecommunications
CEO: Chris Gilbert, 51
Ubiquisys is a pioneer in femtocell technology, which lets mobile-phone users plug into broadband connections to improve their reception while using their handsets at home or in the office. Besides more reliable reception, users can enjoy higher-quality mobile Internet services while taking advantage of cheaper rates. Thirteen mobile operators are currently trying out the service, and three are expected to launch services in Europe by next March.
Mint.com
Mountain View, Calif.
Personal finance services
Founder and CEO: Aaron Patzer, 28
Mint.com makes money by helping consumers make smarter financial decisions. Its four patent-pending technologies and algorithms help users understand where they're spending money, create budgets, and find ways to save. Launched in September 2007, the free online service already has attracted more than 600,000 consumers. Mint.com provides e-mail and text message alerts, notifying users of low account balances and upcoming bills and fees. The company earns its money from referral fees and advertising.
Mojix
Los Angeles
Radio-frequency ID tags
CEO: Ramin Sadr, 49
Mojix was founded in 2004 by a team of former NASA scientists and engineers to apply breakthroughs in deep space communications to radio-frequency ID systems. With traditional systems, RFID tags can't be read unless the scanning device is nearby. Mojix applies new signal-processing technologies to enable long-range detection, even when signals are weak. Mojix's SpaceTime Array Reader claims to deliver a 100,000-times improvement in indoor receiver sensitivity, and can handle numerous applications across an entire factory,
SemiLEDS
Boise, Idaho
Efficient lighting
CEO: Trung Tri Doan, 50
SemiLEDs, with operations in the U.S. and Taiwan, aims to provide the first effective light-emitting-diode (LED) solutions for mass-market lighting. LEDs, though far more efficient than conventional incandescent lighting, until now have been too costly for widespread use. SemiLEDS, founded by a semiconductor industry veteran, tackled the problem by switching to a low-cost chip built on a flexible copper alloy.
Brightcove
Cambridge, Mass.
Broadband media and online video
CEO: Jeremy Allaire, 37
Brightcove has developed an open Web-based software service that allows media groups of all sizes to publish, distribute, and make money from online video through their own Web sites and across the Internet. Hundreds of media companies use its technology to deliver tens of millions of videos to consumers worldwide. The company has raised $91 million from investors including Accel Partners, Allen & Co., Hearst Corp., the New York Times Co., and America Online.
Qifang
Shanghai, China
Finance
CEO: Calvin Chin, 35
Qifang has developed an online microfinance site to help aspiring Chinese university students pay for their schooling. Students who can't afford tuition post their profiles on the site in hopes of catching the attention of well-off individuals or businesses who could lend them money. Qifang brokers the transactions and helps manage the loan portfolios, earning money by charging a 2% fee on each loan.
mPedigree
Accra, Ghana
Anticounterfeiting
CEO: Bright Simons, 27
mPedigree offers consumers a service to instantly verify the authenticity of drugs at the point of purchase. Pharmaceutical companies emboss special codes on drug packaging that are recorded in mPedigree's database. When consumers purchase drugs, they scratch off a panel to reveal the code and send it via text message over a standard mobile phone. Within five seconds, they get a reply indicating whether the code is genuine.
Cows to Kilowatts Partnership Ltd.
Ibadan, Nigeria
Biofuels
CEO: Joseph Adelegan, 41
Cows to Kilowatts has found a clean way to convert slaughterhouse waste into biofuel for household cooking and electricity. Instead of smelly, inefficient traditional waste-treatment methods, Cows to Kilowatts offers a bioreactor system that turns organic waste into cheap, nonpolluting fuel. As a bonus, the system churns out environmentally friendly fertilizer from the remaining sludge.
Nivio
Aigle, Switzerland
Software services
CEO: Sachin Duggal, 25
Need specialized software for a short-term project? No need to buy it; Nivio will rent it to you. The company provides customers with a personalized Windows desktop, outfitted with whatever software they request, for as long as they need it. It also makes a low-cost computing device. The company is about to launch, in partnership with Indian telcom operator Bharti Airtel, a rollout of Internet kiosks across India that will be powered by Nivio.
MorphoSys
Martinsried, Germany
Biotechnology
CEO: Simon Moroney, 49
MorphoSys is trying to reproduce the human immune response in a test tube. The company, which was founded in 1992 and went public on the Frankfurt stock exchange in 1999, boasts a library of more than 10 billion human antibodies that can be optimized to target specific diseases. It has several drugs in phase-one clinical trials, one to combat Alzheimer's disease, two aimed at cancer, and another for arthritis.
JiGrahak Mobility Solutions
Bangalore, India
Mobile commerce
CEO: Sourabh Jain, 31
JiGrahak is behind ngpay, the brand name of a free mobile-commerce service that allows consumers in India to shop, order meals, make charitable donations, do their banking, and pay their bills, among other things. Launched last February, ngpay already has attracted more than 230,000 users and has become the largest channel for mobile-based transactions with Indian Railways and HDFC Bank, and for movie ticketing. The company expects to have 1 million users by mid-2009.
CURRENT Group
Germantown, Md.
Energy efficiency
CEO: Tom Casey, 56
CURRENT provides utility companies with high-speed communications and sensing and analytic software that allows them to manage their grids in real time. Better management yields environmental benefits, too, because electric power generation produces 40% of global carbon-dioxide emissions. CURRENT, founded in 2000, started by offering broadband access via electric lines. It has raised some $300 million from blue chip investors including Google and Goldman Sachs.
GreenPeak Technologies
Utrecht, Netherlands
Green wireless technology
CEO: Cees Links, 51
It sounds like a simple way to save energy: A wireless sensor network in your house would automatically shut off lights and turn down heating when you leave a room. But such networks have proven costly and cumbersome. GreenPeak has developed a communication technology for wireless sensor networks that can use energy harvested from the environment rather than from batteries. It claims to be the first Wi-Fi-based controller capable of providing a maintenance-free sensor network.
Lemnis Lighting
Amsterdam, Netherlands
Lighting
CEO: Frans Otten, 41
Lemnis Lighting was started by Otten and Warner Philips, both great-grandsons of the founder of Royal Philips Electronics. It aims to achieve affordable zero carbon-emission lighting by using light-emitting diodes (LEDs) in new ways. The company is striking deals to have its energy-saving bulbs distributed through electric companies.
Recycla Chile
Santiago, Chile
Recycling
CEO: Fernando Nilo, 44
Recycla Chile was the first company in Latin America to recycle discarded computers, television, mobile phones, fax machines, and other electronic gizmos. Such e-trash accounts for 70% of toxic waste in landfills. Electronics makers collect old devices from business customers and send them to Recycla, which extracts valuable materials. Most of the work is done by former prison inmates, whom the company hires to help them reintegrate into society.
ZPower
Camarillo, Calif.
Batteries
CEO: Ross Dueber, 48
ZPower uses advanced polymers, nanotechnology, power electronics, and processing methods to create a superefficient rechargeable battery for consumer electronic devices. The technology isn't compatible with existing devices that use lithium-ion batteries, but next-generation laptops, mobile phones, and other devices coming to market as early as 2009 will use it. Dueber says Zpower batteries can as much as double the time between recharges.
Virent
Madison, Wis.
Biofuels
Chief technology officer: Randy Cortright, 53
Virent has developed technology to convert plant sugars into hydrocarbon molecules, yielding diesel, jet fuel, chemicals, and other products normally made from petroleum. The company claims its process is more efficient than traditional biofuel methods, such as ethanol fermentation. Virent has raised more than $30 million from investors and is collaborating with Royal Dutch Shell to produce biogasoline.
Alnylam Pharmaceuticals
Cambridge, Mass.
Pharmaceuticals
CEO: John Maraganore, 46
Alnylam is developing a new class of medicines based on a discovery known as RNA interference (RNAi), heralded as a major scientific breakthrough. RNAi is a natural cellular mechanism that can silence specific disease-causing genes. Alnylam is teaming with major drugmakers to develop treatments for liver cancer, Huntington's disease, and other ailments.
AC Immune
Lausanne, Switzerland
Biotechnology
CEO: Andrea Pfeifer, 51
This company, co-founded by a Nobel Laureate in chemistry in 2003, is working on treatments for Alzheimer's disease. Alzheimer's is caused by abnormal aggregations of proteins, called plaques, that block normal brain functioning. AC Immune is developing therapies to dissolve the plaques and inhibit their formation. Clinical trials of three such treatments began this year.
Phase Forward
Waltham, Mass.
Health care
CEO: Robert Weiler, 57
Roughly half of all clinical drug trials still rely on paper recordkeeping. Phase Forward offers software and services to automate the process, reducing the chance of human error and making it easier for researchers to spot potential side effects that emerge during trials. Phase Forward products have already been used by drugmakers and biotech companies in more than 10,000 clinical trials involving 1 million participants.
Intercell
Vienna, Austria
Biotechnology
CEO: Gerd Zettlemeissl, 53
Intercell is developing vaccines that target viruses and bacteria causing a wide range of ailments, from influenza and tuberculosis to Japanese encephalitis. The company analyzes the molecular structures of disease-causing pathogens, then chemically synthesizes them into "smart" vaccines that can help the immune system recognize and kill the pathogens. It also adds "immunizers" that stimulate T-Cells, a type of blood cell that protects the body from infection.
TraceTracker Innovation
Oslo, Norway
Food safety
CEO: Ole-Henning Fredriksen, 45
TraceTracker is creating a kind of global information exchange for the food industry. Its global traceability network, GTNet, enables producers, distributors, and retailers to exchange information about food products, tracing them from raw ingredients to the supermarket shelf. A franchise in Germany which licenses Walt Disney Co.'s brand for use on food products uses GTNet to provide an online tool for consumers, allowing them to use Google Maps to see where ingredients came from.
Proteus Biomedical
Redwood City, Calif.
Medical technology
CEO: Andrew Thompson, 45
Proteus makes tiny microchips implanted in pills that record and transmit how the body reacts. The data is stored temporarily in a patch placed on the patient's skin, then periodically downloaded to the patient's mobile phone so it can be forwarded to the doctor. The system can be used for long-distance monitoring of patients with cardiac problems, as well as making sure that people with infectious diseases or mental illnesses
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